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Lessons Learned in Clinical Trial Communication During an Ebola Outbreak: The Implementation of STRIVE

Lessons Learned in Clinical Trial Communication During an Ebola Outbreak: The Implementation of STRIVE

Author: 
Amy Callis
Victoria M. Carter
Aparna Ramakrishnan
Alison P. Albert
Lansana Conteh
Alhaji Amadu Barrie
Lucian Fahnbulleh
Mark M. Koroma
Samuel Saidu
Otis Williams
Mohamed Samai
Publication Date
Friday, May 18, 2018
Affiliation: 

Centers for Disease Control and Prevention, or CDC (Callis, Carter, Albert); Northrup Grumman (Ramakrishnan); Ministry of Health and Sanitation of Sierra Leone (Conteh, Samai); US Peace Corps (Barrie, Fahnbulleh); eHealth Africa (Koroma, Saidu, Williams); University of Sierra Leone (Samai)

The Ebola outbreak was ongoing in Sierra Leone when the Sierra Leone Trial to Introduce a Vaccine Against Ebola (STRIVE) launched in April 2015, creating a constantly changing environment as the country dealt with a public health emergency. It was against this backdrop that STRIVE developed and implemented a flexible communication strategy to recruit participants, support human subjects' protection, build trust in the community, and mitigate potential rumours and misinformation. This article focuses on the 5 major activities conducted by STRIVE communications team - materials development, sensitisation activities, informational/educational activities, staff communication capacity development, and community engagement - and how those activities were structured and implemented to support human-subjects-protection principles. The article also outlines lessons learned from STRIVE and recommendations for similar clinical trial communication efforts during outbreaks.

  <div class="field button"><a href="https://academic.oup.com/jid/article/217/suppl_1/S40/4999141" target="_blank">Click here to read the article online or to download it in PDF format (8 pages).</a></div>
Contacts (user reference): 
Source: 

The Journal of Infectious Diseases, Volume 217, Issue suppl_1, 18 May 2018, Pages S40–S47, https://doi.org/10.1093/infdis/jix558.

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